February 2021

Two New MSS Sensors for Torque Magnetometry added to Special Developments List

by NANOSENSORS
15 February 202115 March 2023
Inside NANOSENSORS, News & Events, Science & Technology

NANOSENSORS Membrane-type Surface-stress Sensor MSS for torque magnetometry SD-MSS-1KPMAl . Can now be found on the NANOSENSORS Special Developments List

NANOSENSORS™ has completed the development of two additional Membrane-type Surface-stress Sensors (MSS) ( SD-MSS-1KPMAl and SD-MSS-1KPMAu ) dedicated for torque magnetometry. Torque magnetometry is a… Read More »Two New MSS Sensors for Torque Magnetometry added to Special Developments List

Happy New Lunar Year!

by NANOSENSORS
10 February 202115 March 2023
News & Events

NANOSENSORS wishes you all a happy and successful year of the cow. Shiloutte of cows climbing up a hill.

We wish everyone a good start into the year of the bull/ox/cow!

Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

by NANOSENSORS
3 February 202115 March 2023
Science & Technology

Figure 4 from “Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability” by Cyriel Sebastiaan Olie et al. Disrupted cytoskeletal spatial organization in shPAB human muscle cell cultures. A Representative images of control and shPAB human muscle cell cultures, stained with antibodies to tubulin and actin, and the actin filaments were visualized with actin-GFP. B Tubulin staining in control and shPAB myoblast cell cultures after DMSO, 100 nM nocodazole or 25 nM paclitaxel treatment for 2 h. Scale bar is 25 µm. C Measurements of cell-mechanics properties in control and shPAB cells using the Brillouin Light Scattering Microscopy (Ci) or the Atomic Force Microscopy (Cii). Measurements were carried out in myoblasts; every dot represents the median from 1000 measurements in a cell. Cell stiffness is measured by GHz, and the young modulus reports the cell surface tension. Averages and standard deviations are from N = 15 cells. Statistical significance was calculated with the student’s t-test. NANOSENSORS uniqprobe qp-BioAC ( CB3 ) AFM probes were used in the quantitative imaging of cell-mechanics properties where a force curve is applied at each point.

Muscle wasting is connected with changes in various cellular mechanisms that influence protein homeostasis, transcription, protein acetylation and different metabolic pathways. * Scientific studies have… Read More »Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability