Skip to content

Science & Technology

Tipless cantilever arrays – Special Development List updated

NANOSENSORS Special Development List has been updated with completely new items: Tipless cantilevers arrays (qp-TL8) based on uniqprobe – uniform quality probe – technology. Similar to the uniqprobe cantilevers (i.e. qp-CONT), the cantilevers of these new arrays show an outstanding uniformity of their thicknesses leading to a strongly reduced dispersion of force constants and resonance frequenices compared with standard silicon cantilever arrays.

tl8-1

Read More »Tipless cantilever arrays – Special Development List updated

World Science Day

Single pass Kelvin Force Microscopy

Sergei Magonov from NT-MDT captured this extremly impressing single pass Kelvin Force Micoscopy image of self-assemblies of semifluorinated alkanes (F12H12)

KPFM_01

Single-pass Kelvin Force Microscopy (KFM-PM) scan of self-assemblies of semifluorinated alkanes (F12H12) on HOPG. Height, capacitance gradients dC/dZ and dC/dV and surface potential. Images courtesy by Sergei Magonov, obtained with a NT-MDT Titanium scanning probe microscope and a NANOSENSORS PtSi-FM probe.

Read More »World Science Day

Single molecule force spectroscopy with NANOSENSORS™ uniqprobe qp-CONT

High resolution imaging of the cytoplasmic side of bacteriorhodospin (BR) (left) and overlay of 6 force-distance curves (right) showing the controlled C-terminal unfolding of a single BR membrane protein from its native environment.

BR image & spectroscopy

The measurements were recorded in buffer solution with a FlexAFM V3 (Nanosurf) using a NANOSENSORS™ uniqprobe qp-CONT cantilever by Dr. Patrick Frederix from Nanosurf AG.

Read More »Single molecule force spectroscopy with NANOSENSORS™ uniqprobe qp-CONT

Characterization of Interactions between Heparin/Glycosaminoglycan and Adeno-Associated Virus with NANOSENSORS™ Super Sharp Silicon AFM probes

Divergent effect of glycosaminoglycans on the in vitro aggregation of serum amyloid A (http://dx.doi.org/10.1016/j.biochi.2014.05.007). Characterization of Interactions between eparin/Glycosaminoglycan and Adeno-Associated Virus (http://dx.doi.org/10.1021/bi4008676)

Check out the excellent work by Javier Aguilera and his coauthors. The authors used NANOSENSORS Super Sharp Silicon AFM tips to demonstrate awesome morphological features of AAV-2 and complexes with different heparin oligosaccharides and investigated the effect of glycosaminoglycans (GAGs) on the aggregation of serum amyloid A (SAA).

2014-09-18 09_06_46-20140826-142157-Characterization of Interactions between Heparin_Glycosaminoglyc

Read More »Characterization of Interactions between Heparin/Glycosaminoglycan and Adeno-Associated Virus with NANOSENSORS™ Super Sharp Silicon AFM probes