Science & Technology

World Science Day

by NANOSENSORS
10 November 201415 March 2023
Science & Technology

Single pass Kelvin Force Microscopy

Sergei Magonov from NT-MDT captured this extremly impressing single pass Kelvin Force Micoscopy image of self-assemblies of semifluorinated alkanes (F12H12)

Single-pass Kelvin Force Microscopy (KFM-PM) scan of self-assemblies of semifluorinated alkanes (F12H12) on HOPG. Height, capacitance gradients dC/dZ and dC/dV and surface potential. Images courtesy by Sergei Magonov, obtained with a NT-MDT Titanium scanning probe microscope and a NANOSENSORS PtSi-FM probe.

Single molecule force spectroscopy with NANOSENSORS™ uniqprobe qp-CONT

by NANOSENSORS
27 October 201418 March 2024
Science & Technology

High resolution imaging of the cytoplasmic side of bacteriorhodospin (BR) (left) and overlay of 6 force-distance curves (right) showing the controlled C-terminal unfolding of a single BR membrane protein from its native environment.

The measurements were recorded in buffer solution with a FlexAFM V3 (Nanosurf) using a NANOSENSORS™ uniqprobe qp-CONT cantilever by Dr. Patrick Frederix from Nanosurf AG.

Characterization of Interactions between Heparin/Glycosaminoglycan and Adeno-Associated Virus with NANOSENSORS™ Super Sharp Silicon AFM probes

by NANOSENSORS
18 September 201418 March 2024
Science & Technology

Divergent effect of glycosaminoglycans on the in vitro aggregation of serum amyloid A (http://dx.doi.org/10.1016/j.biochi.2014.05.007). Characterization of Interactions between eparin/Glycosaminoglycan and Adeno-Associated Virus (http://dx.doi.org/10.1021/bi4008676)

Check out the excellent work by Javier Aguilera and his coauthors. The authors used NANOSENSORS™ Super Sharp Silicon AFM tips to demonstrate awesome morphological features of AAV-2 and complexes with different heparin oligosaccharides and investigated the effect of glycosaminoglycans (GAGs) on the aggregation of serum amyloid A (SAA).