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Season’s Greetings from NANOSENSORS AFM probes

by NANOSENSORS
22 December 202215 March 2023
News & Events

Illuminated Christmas tree at night time beside an old building

It is again time to wish all users of our AFM probes Happy Holidays! Enjoy the holiday season with friends and family. We are looking… Read More »Season’s Greetings from NANOSENSORS AFM probes

Chemically characterizing the cortical cell nano-structure of human hair using atomic force microscopy integrated with infrared spectroscopy (AFM-IR)

by NANOSENSORS
7 December 202215 March 2023
Science & Technology

Figure 2 from A. P. Fellows et al “Chemically characterizing the cortical cell nano-structure of human hair using atomic force microscopy integrated with infrared spectroscopy (AFM-IR)”: AFM-IR data obtained from a human hair cross-section (approx. 300 nm thick) showing (a) a schematic structural representation of the cortical cell (b) average spectra corresponding to each observed region (macrofibril and Ext-matrix) (c) AFM height map and (d)-(l) IR-intensity maps recorded in contact mode across a 2.5 × 2.5 μm region of the surface at a number of different infrared frequencies corresponding to contributions observed in the spectra (each shown above the corresponding image) for a representative fibre section. NANOSENSORS AdvancedTEC ATEC-CONTAu tip view AFM probes were used.

The structure of hair fibres has been the focus of much research over the last century with several techniques used to investigate their structure. *… Read More »Chemically characterizing the cortical cell nano-structure of human hair using atomic force microscopy integrated with infrared spectroscopy (AFM-IR)

Photoinduced Charge Transfer and Trapping on Single Gold Metal Nanoparticles on TiO2

by NANOSENSORS
28 November 202215 March 2023
Science & Technology

Figure 4 from by “Photoinduced Charge Transfer and Trapping on Single Gold Metal Nanoparticles on TiO2” Monica Luna et al : Topography (top) and VCPD (bottom) images of a 3 nm diameter Au NP on bare TiO2(110) (a) in the dark and (b) under UV illumination. VCPD profiles are shown at the bottom. Color scale in topography: (a) 3.6 nm and (b) 4 nm. A CPD image of a larger sample area can be found in the Supporting Information (Figure S10). NANOSENSORS tip view conductive AdvancedTEC ATEC-EFM AFM probes were used.

Numerous advances of societal significance, such as CO2 conversion to fuels, hydrogen production by water splitting, and new materials with self-cleaning and antifogging properties, are… Read More »Photoinduced Charge Transfer and Trapping on Single Gold Metal Nanoparticles on TiO2

Male-female communication enhances release of extracellular vesicles leading to high fertility in Drosophila

by NANOSENSORS
28 October 202215 March 2023
Science & Technology

Fig. 5 from “Male-female communication enhances release of extracellular vesicles leading to high fertility in Drosophila” by Javier Arturo Sanchez-Lopez et al.: The spermatheca releases EVs with specific characteristics. a–e The spermathecae (SSC > CD63-GFP) were cultured ex vivo to characterize the particles that were released to the spent media: a size distribution of CD63-GFP-positive particles (n = 25 spermathecae from 15 flies) using single-particle tracking of the Nanoimager. b Characterization of CD63-GFP particles by ExoView (100 spermathecae from 50-60 flies) using anti-GFP or anti-CD63. c Representative dSTORM image of EVs found in the spent media of SSC expressing CD63-GFP (n = 25 spermathecae from 15 flies), stained with AlexaFluor555 conjugated anti-CD63 primary antibody. The image shows CD63-GFP-positive EVs and single CD63 AlexaFluor555 molecules the EV’s surface. Scale bars = 1 µm and insets = 20 nm. d–e The morphology of EVs in the spent media was observed by e negative staining in STEM; scale bar = 200 nm; and by d Cryo-TEM; Scale bar = 100 nm (see also Supplementary Fig. 5a-c). f–i The spent media of ex vivo cultured spermathecae were analyzed for the presence of EVs: f Representative AFM scans of SSC-EVs isolated by acoustic sorting (n = 100 spermathecae from 70 flies), showing from left to right: height (nm), adhesion (pN) and Young’s modulus images (MPa). Scale bars = 100 nm (see Supplementary Fig. 5d–g). g–i Single-particle tracking in the nanoimager. g CellMaskTM-positive particle size distribution and concentration profiles of EVs in the spent media of spermathecae incubated in media alone (No ecdy) or with ecdysone (Ecdy) (see also Supplementary Movie 5 for a time lapse of spermathecae end apparatus and endosomal activity post-ecdysone stimulation and methods, ex vivo spermatheca culture section); media with only CellMaskTM stain served as a control for the formation of dye aggregates. h Particle concentration and i mean particle diameter (nm) from g; Box plots are the measurements of particles from four frames of spent media from 25 spermathecae; boxes represent maximum, median and minimum values with outliers; one-way ANOVA, with nonparametric Wilcoxon multiple comparison post-hoc test; *p

The female reproductive tract (female-RT) must decipher the repertoire of molecular cues received from the male during copulation in order to activate and coordinate tract… Read More »Male-female communication enhances release of extracellular vesicles leading to high fertility in Drosophila

First day @Arablab

by NANOSENSORS
24 October 202215 March 2023
News & Events

Meet our CEO at Arablab 2022 and discuss the many applications that are possible using our AFM probes for Atomic Force Microscopy

Meet our CEO @Arablab 2022 in Dubai this week and discuss the many applications that are possible using our #AFMprobes for #AtomicForceMicroscopy

Toward Single-Atomic-Layer Lithography on Highly Oriented Pyrolytic Graphite Surfaces Using AFM-Based Electrochemical Etching

by NANOSENSORS
9 October 202215 March 2023
Science & Technology

Figure 2 from Wei Han et al. “Toward Single-Atomic-Layer Lithography on Highly Oriented Pyrolytic Graphite Surfaces Using AFM-Based Electrochemical Etching” Schematic diagram of the AFM-based electrochemical etching apparatus with an RH-controlled environment. The experiments were performed under ambient conditions with a commercial atomic force microscope using NANOSENSORS PtIr5 coated PointProbePlus® PPP-EFM AFM probes. The AFM tip side coating enhances the conductivity of the AFM tip and allows electrical contacts, and the opposite side coating enhances the laser reflex.

Happy #NanotechnologyDay! The date, 10/9, is a nod to the nanometer scale, where objects span only billionths of a meter (10⁻⁹ meters). We celebrate it… Read More »Toward Single-Atomic-Layer Lithography on Highly Oriented Pyrolytic Graphite Surfaces Using AFM-Based Electrochemical Etching

Magnetic Skyrmions in a Thickness Tunable 2D Ferromagnet from a Defect Driven Dzyaloshinskii–Moriya Interaction

by NANOSENSORS
23 September 202215 March 2023
Science & Technology

Figure 4 from “Magnetic Skyrmions in a Thickness Tunable 2D Ferromagnet from a Defect Driven Dzyaloshinskii–Moriya Interaction” by Anirban Chakraborty et al. Thickness dependence of skyrmion size in lamella L2 as imaged by MFM. a) SEM image of the wedge-shaped lamella. The thickness of the lamella varies from ≈100 nm to ≈2 µm. b) MFM image of skyrmions in the lamella at 100 K and 0.032 T. c–f) Evolution of skyrmions as the field is increased from 0.1 to 0.2 T and finally reaches the field polarized state at ≈0.3 T. The blue and red contrast in the MFM images represent up- and down-magnetized domains. All MFM images are at the same scale: a scale bar is shown in (b). g) Skyrmion diameter as a function of lamella thickness including both MFM and LTEM data. NANOSENSORS SSS-MFMR AFM probes for magnetic force microscopy were used for all MFM measurements.

There is considerable interest in van der Waals (vdW) materials as potential hosts for chiral skyrmionic spin textures. Of particular interest is the ferromagnetic, metallic… Read More »Magnetic Skyrmions in a Thickness Tunable 2D Ferromagnet from a Defect Driven Dzyaloshinskii–Moriya Interaction

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