AFM Tips

Happy New Lunar Year!

by NANOSENSORS
31 January 202215 March 2023
News & Events

NANOSENSORS AFM probes lunar new year image 2022. A shilouette of a tiger waling through a forest

We wish everyone a good start into the year of the tiger!

Season’s Greetings from NANOSENSORS AFM probes

by NANOSENSORS
20 December 202115 March 2023
News & Events

The snowman wishes everyone Merry Christmas and a Happy New Year.

There is a snowman in the park! This is a sure sign that it is again time to wish all users of our AFM probes… Read More »Season’s Greetings from NANOSENSORS AFM probes

Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds

by NANOSENSORS
29 October 202115 March 2023
Science & Technology

Figure 3 from “Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds AFM imaging and spectrometry measurement” by Ashlee F. Harris et al.: They used AFM surface topography measurements to confirm that the structures such as plant vasculature were preserved after the scSO2 process and used AFM force curves to calculate the Young’s Modulus (YM) of the scCO2 decellularized scaffold. NANOSENSORS uniqprobe qp-BioAC AFM probes were used for the described AFM measurments. (a) Representative false colored three-dimensional surface mapping images and (b) Young’s modulus of scCO2 and chemically decellularized scaffolds (data as mean ± SEM; n = 5).

Biocompatible scaffolds that can be repopulated with human cells have many uses such serving as replacement organs and tissues. Therefore there is an increasing interest… Read More »Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds

Happy Swiss National Holiday with Smallest Swiss Cross

by NANOSENSORS
31 July 202115 March 2023
News & Events

We are celebrating today’s Swiss National Holiday courtesy of Basel University with the Smallest Swiss Cross – Made of 20 Single Atoms ( a NANOSENSORS… Read More »Happy Swiss National Holiday with Smallest Swiss Cross

Signal Origin of Electrochemical Strain Microscopy and Link to Local Chemical Distribution in Solid State Electrolytes

by NANOSENSORS
19 April 202115 March 2023
Science & Technology

Figure 1 from Nino Schön et al. «Signal Origin of Electrochemical Strain Microscopy and Link to Local Chemical Distribution in Solid State Electrolytes”: a) Topography, b) deflection error, and c) corresponding cantilever deflection change (Dac) map of a 30 µm × 30 µm area of LATP. d) Noncontact EFM amplitude map in the same area. NANOSENSORS conductive platinum-iridium coated PointProbe Plus PPP-EFM AFM probes were used.

Solid state electrolytes (SSEs) are interesting materials that could potentially replace the currently used organic electrolytes in lithium‐ion batteries (LIBs). * Electrochemical strain microscopy (ESM),… Read More »Signal Origin of Electrochemical Strain Microscopy and Link to Local Chemical Distribution in Solid State Electrolytes

Happy New Lunar Year!

by NANOSENSORS
10 February 202115 March 2023
News & Events

NANOSENSORS wishes you all a happy and successful year of the cow. Shiloutte of cows climbing up a hill.

We wish everyone a good start into the year of the bull/ox/cow!

Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

by NANOSENSORS
3 February 202115 March 2023
Science & Technology

Figure 4 from “Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability” by Cyriel Sebastiaan Olie et al. Disrupted cytoskeletal spatial organization in shPAB human muscle cell cultures. A Representative images of control and shPAB human muscle cell cultures, stained with antibodies to tubulin and actin, and the actin filaments were visualized with actin-GFP. B Tubulin staining in control and shPAB myoblast cell cultures after DMSO, 100 nM nocodazole or 25 nM paclitaxel treatment for 2 h. Scale bar is 25 µm. C Measurements of cell-mechanics properties in control and shPAB cells using the Brillouin Light Scattering Microscopy (Ci) or the Atomic Force Microscopy (Cii). Measurements were carried out in myoblasts; every dot represents the median from 1000 measurements in a cell. Cell stiffness is measured by GHz, and the young modulus reports the cell surface tension. Averages and standard deviations are from N = 15 cells. Statistical significance was calculated with the student’s t-test. NANOSENSORS uniqprobe qp-BioAC ( CB3 ) AFM probes were used in the quantitative imaging of cell-mechanics properties where a force curve is applied at each point.

Muscle wasting is connected with changes in various cellular mechanisms that influence protein homeostasis, transcription, protein acetylation and different metabolic pathways. * Scientific studies have… Read More »Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

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