Atomic Force Microscopy

Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

by NANOSENSORS
3 February 202115 March 2023
Science & Technology

Figure 4 from “Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability” by Cyriel Sebastiaan Olie et al. Disrupted cytoskeletal spatial organization in shPAB human muscle cell cultures. A Representative images of control and shPAB human muscle cell cultures, stained with antibodies to tubulin and actin, and the actin filaments were visualized with actin-GFP. B Tubulin staining in control and shPAB myoblast cell cultures after DMSO, 100 nM nocodazole or 25 nM paclitaxel treatment for 2 h. Scale bar is 25 µm. C Measurements of cell-mechanics properties in control and shPAB cells using the Brillouin Light Scattering Microscopy (Ci) or the Atomic Force Microscopy (Cii). Measurements were carried out in myoblasts; every dot represents the median from 1000 measurements in a cell. Cell stiffness is measured by GHz, and the young modulus reports the cell surface tension. Averages and standard deviations are from N = 15 cells. Statistical significance was calculated with the student’s t-test. NANOSENSORS uniqprobe qp-BioAC ( CB3 ) AFM probes were used in the quantitative imaging of cell-mechanics properties where a force curve is applied at each point.

Muscle wasting is connected with changes in various cellular mechanisms that influence protein homeostasis, transcription, protein acetylation and different metabolic pathways. * Scientific studies have… Read More »Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

In‐situ force measurement during nano‐indentation combined with Laue microdiffraction

by NANOSENSORS
22 January 202115 March 2023
Science & Technology

image of a tuning fork based NANOSENSORS self-sensing and self-actuating Akiyama-probe (A-probe)

A NANOSENSORS™ self-sensing self-activating Akiyama probe was used in a home-built Scanning Probe Microscope for this interesting research article. *Florian Lauraux, Sarah Yehya, Stéphane Labat,… Read More »In‐situ force measurement during nano‐indentation combined with Laue microdiffraction

Yeast Nanometric Scale Oscillations Highlights Fibronectin Induced Changes in C. Albicans

by NANOSENSORS
18 October 202015 March 2023
Science & Technology

Supplementary Figure S2 from “Yeast Nanometric Scale Oscillations Highlights Fibronectin Induced Changes in C. Albicans” by Anne-Céline Kohler et al.: Density of yeast cells on AFM cantilever at the start of the experiment (A) and at the end of the experiment (B). The size of the AFM cantilever is 40 by 130 μm. NANOSENSORS tipless uniqprobe SD-qp-CONT-TL AFM probes from the NANOSENSORS Special Developments List were used in the in-house developed nanomotion detection device.

Yeast resistance to antifungal drugs is a major public health issue. Fungal adhesion onto the host mucosal surface is still a partially unknown phenomenon that… Read More »Yeast Nanometric Scale Oscillations Highlights Fibronectin Induced Changes in C. Albicans

Multi-Channel Exploration of O Adatom on TiO2(110) Surface by Scanning Probe Microscopy

by NANOSENSORS
5 October 202015 March 2023
Science & Technology

Figure 5. from “Multiple images of TiO2(110) surface with atomic resolution and corresponding line profiles” by Huan Fei Wen et al. (a) Frequency shift (∆f) image, (b) tunneling current () image and (c) local contact potential difference (VLCPD) image. (d,e) The line profiles along the blue line on the surface in (b,c). (f0 = 805 kHz, Q = 27623, ∆f = −260 Hz, VDC = 1.3 V, VAC = 1.5 V, A = 500 pm, size: 3.5 × 3.2 nm2). Multiple images of TiO2(110) surface with atomic resolution and corresponding line profiles. (a) Frequency shift (∆f) image, (b) tunneling current () image and (c) local contact potential difference (VLCPD) image. (d,e) The line profiles along the blue line on the surface in (b,c). (f0 = 805 kHz, Q = 27623, ∆f = −260 Hz, VDC = 1.3 V, VAC = 1.5 V, A = 500 pm, size: 3.5 × 3.2 nm2). - Ultrastiff NANOSENSORS SD-T10L100 AFM probes were used.

In the article “Multi-Channel Exploration of O Adatom on TiO2(110) Surface by Scanning Probe Microscopy” Huan Fei Wen, Yasuhiro Sugawara and Yan Jun describe how… Read More »Multi-Channel Exploration of O Adatom on TiO2(110) Surface by Scanning Probe Microscopy

Macroscopic manifestation of domain-wall magnetism and magnetoelectric effect in a Néel-type skyrmion host

by NANOSENSORS
20 September 202015 March 2023
Science & Technology

Supplementary Figure 1 a – d from “Macroscopic manifestation of domain-wall magnetism and magnetoelectric effect in a Néel-type skyrmion host” by K. Geirhos et al: Typical ferroelectric do-main pattern observed on the (001) cleaved GaV4Se8 crystal surface atT=10 K. a, The topography is characterized by stripes roughly parallel to the [110] axis and folds parallel to the [010] axis. The latter originate in the differently oriented distortion of the ferroelastic domains. The color scale corresponds to the z-displacement of the tip. b ,In the dissipation channel of the nc-AFM every second domain appears bright. For the non-magnetic tip the dissipation originates from electric interactions. The dissipated power is indicated by the color scale. Please have a look at the full article to view the full supplementary figure. NANOSENSORS Platinum Silicide PtSi-FM AFM probes were used for the imaging.

In the article “Macroscopic manifestation of domain-wall magnetism and magnetoelectric effect in a Néel-type skyrmion host” Korbinian Geirhos, Boris Gross, Bertalan G. Szigeti, Andrea Mehlin,… Read More »Macroscopic manifestation of domain-wall magnetism and magnetoelectric effect in a Néel-type skyrmion host

Electric-field-driven non-volatile multi-state switching of individual skyrmions in a multiferroic heterostructure

by NANOSENSORS
24 August 202015 March 2023
Science & Technology

Figure 2 from “Electric-field-driven non-volatile multi-state switching of individual skyrmions in a multiferroic heterostructure” by Yadong Wang et al.: Electric-field-induced switching of individual skyrmion. The transferred average strain εave and corresponding magnetic domain evolution processes in the d ~ 350 nm a [Pt/Co/Ta]12 and b [Pt/Co/Ta]8 nano-dots in a cycle of E ranging from +10 to −10 kV cm−1. Positive εave (red dots) represents tensile strain while negative εave (blue dots) represents compressive strain. μ0H represents the external magnetic field except that from the MFM tip and here μ0H is equal to be 0 mT. The inset of b illustrates the spin texture of the magnetic domain that is encompassed by the red box. The stripe domain enclosed by the black box shows the initial state of the magnetic domain evolution path. The gray dots represent the corresponding electric field for the MFM images. The MFM contrast represents the MFM tip resonant frequency shift (Δf). The scale bar represents 250 nm. NANOSENSORS™ PPP-LM-MFMR low moment magnetic AFM probes were used

Electrical manipulation of skyrmions attracts considerable attention for its rich physics and promising applications. To date, such a manipulation is realized mainly via spin-polarized current… Read More »Electric-field-driven non-volatile multi-state switching of individual skyrmions in a multiferroic heterostructure

Insights into dynamic sliding contacts from conductive atomic force microscopy

by NANOSENSORS
12 August 202015 March 2023
Science & Technology

Figure 1 (a) from “Insights into dynamic sliding contacts from conductive atomic force microscopy” by Nicholas Chan et al: A schematic of the experimental setup is shown in Fig. 1(a). The experiment was conducted using an ultra-high vacuum (UHV)AFM at room temperature at a pressure of

Friction in nanoscale contacts is determined by the size and structure of the interface that is hidden between the contacting bodies. One approach to investigating… Read More »Insights into dynamic sliding contacts from conductive atomic force microscopy