biology

Efficient long-range conduction in cable bacteria through nickel protein wires

by NANOSENSORS
27 June 202215 March 2023
Science & Technology

Bio-materials typically have an intrinsically low electrical conductivity, and so the availability of a bio-material with extraordinary electrical properties has great potential for new applications… Read More »Efficient long-range conduction in cable bacteria through nickel protein wires

Cerosomes as skin repairing agent: Mode of action studies with a model stratum corneum layer at liquid/air and liquid/solid interfaces

by NANOSENSORS
23 March 202215 March 2023
Science & Technology

Fig. 7 from “Cerosomes as skin repairing agent: Mode of action studies with a model stratum corneum layer at liquid/air and liquid/solid interfaces” by F. Strati et al: AFM scans of a) SC model monolayer transferred via LB method onto mica support, b) SC model monolayer after injection of cerosomes, c) SC model monolayer after injection of cerosome + S75-3 formulation, and d) SC model monolayer after injection of S75-3 liposomal formulation. All samples were transferred via the LS method onto glass substrate. Each experiment was performed at 20°C and the subphase used for a) was Millipore water while for b), c), and d) the same aqueous solutions have been used as for the formulation of the liposomes. Topographical images were recorded in liquid state using NANOSENSORS uniqprobe qp-BioT AFM probes in a standard liquid cell containing the needed buffer.

The human skin is the second largest organ of the human body. The stratum corneum (SC) is the outmost layer of the human skin and… Read More »Cerosomes as skin repairing agent: Mode of action studies with a model stratum corneum layer at liquid/air and liquid/solid interfaces

Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds

by NANOSENSORS
29 October 202115 March 2023
Science & Technology

Figure 3 from “Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds AFM imaging and spectrometry measurement” by Ashlee F. Harris et al.: They used AFM surface topography measurements to confirm that the structures such as plant vasculature were preserved after the scSO2 process and used AFM force curves to calculate the Young’s Modulus (YM) of the scCO2 decellularized scaffold. NANOSENSORS uniqprobe qp-BioAC AFM probes were used for the described AFM measurments. (a) Representative false colored three-dimensional surface mapping images and (b) Young’s modulus of scCO2 and chemically decellularized scaffolds (data as mean ± SEM; n = 5).

Biocompatible scaffolds that can be repopulated with human cells have many uses such serving as replacement organs and tissues. Therefore there is an increasing interest… Read More »Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds

Yeast Nanometric Scale Oscillations Highlights Fibronectin Induced Changes in C. Albicans

by NANOSENSORS
18 October 202015 March 2023
Science & Technology

Supplementary Figure S2 from “Yeast Nanometric Scale Oscillations Highlights Fibronectin Induced Changes in C. Albicans” by Anne-Céline Kohler et al.: Density of yeast cells on AFM cantilever at the start of the experiment (A) and at the end of the experiment (B). The size of the AFM cantilever is 40 by 130 μm. NANOSENSORS tipless uniqprobe SD-qp-CONT-TL AFM probes from the NANOSENSORS Special Developments List were used in the in-house developed nanomotion detection device.

Yeast resistance to antifungal drugs is a major public health issue. Fungal adhesion onto the host mucosal surface is still a partially unknown phenomenon that… Read More »Yeast Nanometric Scale Oscillations Highlights Fibronectin Induced Changes in C. Albicans

Plant-Based Scaffolds Modify Cellular Response to Drug and Radiation Exposure Compared to Standard Cell Culture Models

by NANOSENSORS
7 September 202015 March 2023
Science & Technology

Plant-based scaffolds present many advantages over a variety of biomaterials.* Recent studies explored their potential to be repopulated with human cells and thus highlight a… Read More »Plant-Based Scaffolds Modify Cellular Response to Drug and Radiation Exposure Compared to Standard Cell Culture Models

Soft, drift-reduced AFM cantilevers for Biology and Life Sciences – Uniqprobe Screencast passes the 1000 views mark

by NANOSENSORS
6 August 202015 March 2023
Inside NANOSENSORS, News & Events, Videos

The screencast on the soft, drift-reduced NANOSENSORS™ uniqprobe cantilevers for biology and life science applications held by Dr. Laure Aeschimann has just passed the 1000… Read More »Soft, drift-reduced AFM cantilevers for Biology and Life Sciences – Uniqprobe Screencast passes the 1000 views mark

Simultaneous co-localized super-resolution fluorescence microscopy and atomic force microscopy: combined SIM and AFM platform for the life sciences

by NANOSENSORS
9 June 202015 March 2023
Science & Technology

Figure 4 a and b from Ana I. Gómez-Varela et al “Simultaneous co-localized super-resolution fluorescence microscopy and atomic force microscopy: combined SIM and AFM platform for the life sciences : Simultaneous SR-SIM/AFM acquisition. The AFM measurements were carried out on fixed U2OS cells in medium/buffer with (a) and without N-SIM illumination (b). For convenience and enhanced feature/noise contrast, both AFM topography images in the SR-SIM/AFM overlays are displayed with an edge detection algorithm using a pixel difference operator in X. The topography images from Petri dish surface on three positions (labelled in the figures) were planefit (1st order polynomial function) to compensate for tilts in the sample surface, and subjected to surface roughness analysis Please have a look at the full article to view the full figure. https://rdcu.be/b4Iot

Correlating data from different microscopy techniques holds the potential to discover new facets of signalling events in cellular biology.* In the article “Simultaneous co-localized super-resolution… Read More »Simultaneous co-localized super-resolution fluorescence microscopy and atomic force microscopy: combined SIM and AFM platform for the life sciences