tissue engineering

Lipoplex-Functionalized Thin-Film Surface Coating Based on Extracellular Matrix Components as Local Gene Delivery System to Control Osteogenic Stem Cell Differentiation

Figure 5 from Catharina Husteden et al. 2023 “Lipoplex-Functionalized Thin-Film Surface Coating Based on Extracellular Matrix Components as Local Gene Delivery System to Control Osteogenic Stem Cell Differentiation”: A–D) Topography images [Cs/Col]4Cs (A), [Cs/Col]4Cs/LPX (B), [Cs/Col]4Cs/LPX/Cs (C), and [Cs/Col]4Cs/LPX/Cs/Col determined by AFM [Scale bar 1 µm] (D). E) Distribution curves of Young's modulus (E0) with a force map of a defined area (see also Figure S4, Supporting Information of the cited article). NANOSENSORSTM uniqprobe triangular qp-BioT AFM probes were used for the quantitative imaging to investigate the surface roughness and topography (in a standard liquid cell of a commercially available atomic force microscope) and force mapping. The uniqprobe qp-BioT AFM probe types offer an alternative to silicon nitride probes, with the advantage of taller AFM tips with smaller opening angles and reduced thermal drift.

The development of smart multifunctional biomaterials with the ability to control the behavior of stem cells on demand has become a powerful strategy in regenerative… Read More »Lipoplex-Functionalized Thin-Film Surface Coating Based on Extracellular Matrix Components as Local Gene Delivery System to Control Osteogenic Stem Cell Differentiation

Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds

by NANOSENSORS
29 October 202115 March 2023
Science & Technology

Figure 3 from “Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds AFM imaging and spectrometry measurement” by Ashlee F. Harris et al.: They used AFM surface topography measurements to confirm that the structures such as plant vasculature were preserved after the scSO2 process and used AFM force curves to calculate the Young’s Modulus (YM) of the scCO2 decellularized scaffold. NANOSENSORS uniqprobe qp-BioAC AFM probes were used for the described AFM measurments. (a) Representative false colored three-dimensional surface mapping images and (b) Young’s modulus of scCO2 and chemically decellularized scaffolds (data as mean ± SEM; n = 5).

Biocompatible scaffolds that can be repopulated with human cells have many uses such serving as replacement organs and tissues. Therefore there is an increasing interest… Read More »Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds

Plant-Based Scaffolds Modify Cellular Response to Drug and Radiation Exposure Compared to Standard Cell Culture Models

by NANOSENSORS
7 September 202015 March 2023
Science & Technology

Plant-based scaffolds present many advantages over a variety of biomaterials.* Recent studies explored their potential to be repopulated with human cells and thus highlight a… Read More »Plant-Based Scaffolds Modify Cellular Response to Drug and Radiation Exposure Compared to Standard Cell Culture Models

Graphene-Reinforced Biodegradable Resin Composites for Stereolithographic 3D Printing of Bone Structure Scaffolds

by NANOSENSORS
7 July 201915 March 2023
Science & Technology

UV-crosslinkable graphene-reinforced biodegradable nanocomposites using SLA 3D printing technology can potentially remove important cost barriers for personalized biological tissue engineering as compared to the traditional… Read More »Graphene-Reinforced Biodegradable Resin Composites for Stereolithographic 3D Printing of Bone Structure Scaffolds