uniqprobe

Substrate properties modulate cell membrane roughness by way of actin filaments

by NANOSENSORS
4 January 201915 March 2023
Science & Technology

Supplementary Figure S1 from Chao-Hung Chang et al. “Substrate properties modulate cell membrane roughness by way of actin filaments”: Images of membrane topography determined by atomic force microscopy (AFM). MEFs were seeded on the polymer coverslip-bottom μ-dishes coated with 0 or 10 μg/ml FN for 6 hours for the measurement of membrane roughness by AFM. The regions marked by the white squares in the bright-field images are displayed in the membrane topography. Scale bar, 10 μm. NANOSENSORS uniqprobe qp-SCONT AFM probes(long cantilever length 125 um, spring constant 0.01 N/m) were used.

“Cell membrane roughness has been proposed as a sensitive feature to reflect cellular physiological conditions”* In the article “Substrate properties modulate cell membrane roughness by… Read More »Substrate properties modulate cell membrane roughness by way of actin filaments

Get free NANOSENSORS qp-fast AFM probes at booth 610 at MRS Fall 2018

by NANOSENSORS
27 November 201815 March 2023
News & Events

NANOSENSORS uniqprobe qp-fast AFM probe

Are you looking for AFM probes with unsurpassed small variation in spring constant and resonance frequency? Then visit the NanoAndMore USA booth no. 610 at… Read More »Get free NANOSENSORS qp-fast AFM probes at booth 610 at MRS Fall 2018

A fibrin biofilm covers blood clots and protects from microbial invasion

by NANOSENSORS
28 October 201815 March 2023
Science & Technology

Supplemental Figure. 6. From Macrea et. al “A fibrin biofilm covers blood clots and protects from microbial invasion” Mechanisms and roles of fibrin film. A, Sneddon model used to calculate Young’s Modulus, where F is the force from the force curve, E is Young’s modulus, ν is Poisson’s ratio (0.5), α is the half angle for the indenter (15 degrees for our tips), and δ is the indentation. Note that this equation is only accurate with a half angle of 15 degrees for the first 200nm of indentation. B, Strength of the fibrin film in clots produced with plasma and thrombin with or without T101 (FXIII inhibitor ) investigated using atomic force microscopy (AFM). Fibrin fibres were visible under the film surface and these areas presented with stiffer Young’s modulus than fibrin film suspended between fibres. Grey lines in the zoomed-in images represent Young’s modulus scan area represented in the line force graphs. Scale bar - 2μm. C, Young’s Modulus was calculated for the suspended film and the film supported by fibers with and without T101 by fitting a Sneddon model to all AFM force curves found over the entire area that was imaged. 20 measurements were taken for each condition. **** P

New interesting publication by Macrea et. al mentioning the use of NANOSENSORS uniqprobe qp-BioAC: “Hemostasis requires conversion of fibrinogen to fibrin fibers that generate a… Read More »A fibrin biofilm covers blood clots and protects from microbial invasion

Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils

by NANOSENSORS
15 August 201815 March 2023
Science & Technology

Figure 5 from Yordanova et. al. "Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils" - AFM image of the Zn2+: GnRH [6-D-Phe] 10:1 complex. (a,b) Oligomers after preparation with tapping mode in Tris buffer solution (c,d) fibrils with tapping mode in air (z-scale indicates the average size of the formed oligomers and fibrils). NANOSENSORS qp-BioAC AFM probe was used to perform images in buffer solution

For this article the AFM images taken with tapping mode in Tris buffer solution were performed with the NANOSENSORS qp-BioAC (cantilever 3, resonance frequency 30kHz).… Read More »Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils

Learn more about our new AFM probes at ISPM 2018

by NANOSENSORS
11 May 201815 March 2023
News & Events

NanoAndMore USA table at the International Scanning Probe Microscopy 2018 conference at Arizona State University in Tempe Arizona

It is the last day if the International Scanning Probe Microscopy (ISPM) 2018 conference in Tempe, Arizona. Don’t forget to pass by the NanoAndMore USA… Read More »Learn more about our new AFM probes at ISPM 2018

Near-Field Plasmonic probe with Super Resolution and High Throughput and Signal-to-Noise Ratio

by NANOSENSORS
4 February 201818 March 2024
Science & Technology

Plasmonic AFM tip using a quartz-like NANOSENSORS qp-CONT as basis, as described in: Ruei-Han Jiang et Al., Near-Field Plasmonic Probe with Super Resolution and High Throughput and Signal-to-Noise Ratio, Nano Letters Article ASAP DOI: 10.1021/acs.nanolett.7b04142, image courtesy of Ruei-Han Jiang, Department of Materials Science and Engineering National Tsing Hua University

In the recently published article “New-Field Plasmonic probe with Super Resolution and High Throughput and Signal-to-Noise Ratio” by Ta-Jen Yen et. Al. a plasmonic tip… Read More »Near-Field Plasmonic probe with Super Resolution and High Throughput and Signal-to-Noise Ratio

NANOSENSORS this week at 2017 MRS Fall Exhibit

by NANOSENSORS
28 November 201715 March 2023
News & Events

NANOSENSORS AFM probes at the NanoAndMore USA booth no. 610 2017 MRS Fall Exhibit

Visit us at the NanoAndMore USA booth no. 610 at the 2017 MRS Fall Exhibit this week to learn more about three newly introduced Uniqprobe… Read More »NANOSENSORS this week at 2017 MRS Fall Exhibit