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uniqprobe

Tipless cantilever arrays – Special Development List updated

NANOSENSORS Special Development List has been updated with completely new items: Tipless cantilevers arrays (qp-TL8) based on uniqprobe – uniform quality probe – technology. Similar to the uniqprobe cantilevers (i.e. qp-CONT), the cantilevers of these new arrays show an outstanding uniformity of their thicknesses leading to a strongly reduced dispersion of force constants and resonance frequenices compared with standard silicon cantilever arrays.

tl8-1

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Single molecule force spectroscopy with NANOSENSORS™ uniqprobe qp-CONT

High resolution imaging of the cytoplasmic side of bacteriorhodospin (BR) (left) and overlay of 6 force-distance curves (right) showing the controlled C-terminal unfolding of a single BR membrane protein from its native environment.

BR image & spectroscopy

The measurements were recorded in buffer solution with a FlexAFM V3 (Nanosurf) using a NANOSENSORS™ uniqprobe qp-CONT cantilever by Dr. Patrick Frederix from Nanosurf AG.

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