SSS-SEIHR

Cantilever data:
Property Nominal Value Specified Range
Resonance Frequency [kHz] 130 96 - 175
Force Constant [N/m] 15 5 - 37
Length [µm] 225 215 - 235
Mean Width [µm] 33 25 - 40
Thickness [µm] 5 4 - 6
Order codes and shipping units:
Order Code AFM probes per pack Data sheet
SSS-SEIHR-10 10 of all probes
SSS-SEIHR-20 20 of all probes
SSS-SEIHR-50 50

Special handling information for NANOSENSORS™

Due to their unique geometry the tips of the are more susceptible to tip damage by electrostatic discharge (ESD) than other Silicon-SPM-Probes.

Electric fields near the probe chip may lead to field evaporation which can blunt the tip apex of the probe tip. Therefore the NANOSENSORS™ are shipped in specially designed ESD-safe chip carriers.

NANOSENSORS™ recommends to their customers to take appropriate precautions to avoid tip damage due to electrostatic discharge when handling the probes. This can for example be done by using anti-electrostatic mats, wrist bands and tweezers.

NANOSENSORS™ SuperSharpSilicon

SuperSharpSilicon™ - SEIKO Microscopes - Non-Contact / Tapping Mode - High Force Constant - Reflex Coating

For owners of a Seiko Instruments microscope using the non-contact mode we recommend the NANOSENSORS™ SEIH type (Seiko Instruments / high force constant). Compared with the ZEIH type the force constant is further reduced.

For enhanced resolution of nanostructures and microroughness we offer our SuperSharpSilicon™ AFM tip with unrivalled sharpness.

The AFM probe offers unique features:

  • guaranteed AFM tip radius of curvature < 5 nm
  • typical AFM tip radius of curvature of 2 nm
  • typical aspect ratio at 200 nm from AFM tip apex in the order of 4:1
  • half cone angle at 200 nm from apex < 10°
  • highly doped silicon to dissipate static charge
  • high mechanical Q-factor for high sensitivity
  • alignment grooves on backside of silicon holder chip
  • precise alignment of the AFM cantilever position (within +/- 2 µm) when used with the Alignment Chip
  • compatible with PointProbe® Plus XY-Alignment Series

The reflective coating is an approximately 30 nm thick aluminum coating on the detector side of the AFM cantilever which enhances the reflectivity of the laser beam by a factor of about 2.5. Furthermore it prevents light from interfering within the AFM cantilever. As the coating is nearly stress-free the bending of the AFM cantilever due to stress is less than 2 degrees.

This AFM probe features alignment grooves on the back side of the holder chip. These grooves fit to the NANOSENSORS Alignment Chip.


Dennis K. Galanakis, Anna Protopopova, Kao Li, Yingjie Yu, Tahmeena Ahmed, Lisa Senzel, Ryan Heslin, Mohamed Gouda, Jaseung Koo, John Weisel, Marilyn Manco-Johnson and Miriam Rafailovich
Novel characteristics of soluble fibrin: hypercoagulability and acceleration of blood sedimentation rate mediated by its generation of erythrocyte-linked fibers
Cell and Tissue Research (2022)
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Dennis K. Galanakis, Anna Protopopova, Liudi Zhang, Kao Li, Clement Marmorat, Tomas Scheiner, Jaseung Koo, Anne G. Savitt, Miriam Rafailovich and John Weisel
Fibers Generated by Plasma Des-AA Fibrin Monomers and Protofibril/Fibrinogen Clusters Bind Platelets: Clinical and Nonclinical Implications
TH Open 2021; 05(03): e273-e285
DOI: 10.1055/s-0041-1725976


Jiang Yang, Tai Wang, Lina Zhao, Vinagolu K. Rajasekhar, Suhasini Joshi, Chrysafis Andreou, Suchetan Pal, Hsiao-ting Hsu, Hanwen Zhang, Ivan J. Cohen, Ruimin Huang, Ronald C. Hendrickson, Matthew M. Miele, Wenbo Pei, Matthew B. Brendel, John H. Healey, Gabriela Chiosis, and Moritz F. Kircher
Gold/alpha-lactalbumin nanoprobes for the imaging and treatment of breast cancer
Nature Biomedical Engineering 4, pages 686–703 (2020)
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Anna D. Protopopova, Andrea Ramirez, Dmitry V. Klinov, Rustem I. Litvinov, John W. Weisel
Factor XIII topology: organization of B subunits and changes with activation studied with single-molecule atomic force microscopy
Journal of Thrombosis and Haemostasis, Volume 17, Issue 5, May 2019, Pages 737-748
DOI: https://doi.org/10.1111/jth.14412


Santu Bera, Sudipta Mondal, Bin Xue, Linda J. W. Shimon, Yi Cao and Ehud Gazit
Rigid helical-like assemblies from a self-aggregating tripeptide
Nature Materials volume 18, pages 503–509 (2019)
DOI: https://doi.org/10.1038/s41563-019-0343-2


Chao Liang, Zonghuang Ye, Bin Xue, Ling Zeng, Wenjian Wu, Chao Zhong, Yi Cao*, Biru Hu*, and Phillip B Messersmith
Self-Assembled Nanofibers for Strong Underwater Adhesion: The Trick of Barnacles
ACS Applied Materials and Interfaces 2018, 10, 30, 25017–25025
DOI: https://doi.org/10.1021/acsami.8b04752


Anna D. Protopopova, Rustem I. Litvinov, Dennis K. Galanakis, Chandrasekaran Nagaswami, Nikolay A. Barinov, Alexander R. Mukhitov, Dmitry V. Klinov and John W. Weisela
Morphometric characterization of fibrinogen’s αC regions and their role in fibrin self-assembly and molecular organization
Nanoscale. 2017 Sep 21; 9(36): 13707–13716.
DOI: 10.1039/c7nr04413e


Artem Zhmurov, Anna D.Protopopova, Rustem I. Litvinov, Pavel Zhukov, Alexander R.Mukhitov, John W. Weisel, Valeri Barsegov
Structural Basis of Interfacial Flexibility in Fibrin Oligomers
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Annalisa Calò, Aitziber Eleta-Lopez, Pablo Stoliar, David De Sancho, Sergio Santos, Albert Verdaguer and Alexander M. Bittner
Multifrequency Force Microscopy of Helical Protein Assembly on a Virus
Nature Scientific Reports volume 6, Article number: 21899 (2016)
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